Patent for a method for studying the microbiota of the large intestine

Alphalab has received a patent for a real‑time PCR method for studying intestinal microbiota and has released the Colonoflor reagent kit.

Epithelial tissues
Photo by Bioscience Image Library by Fayette Reynolds on Unsplash

Alphalab has received a patent for a method for studying colon microbiota using real‑time fluorescence detection and the Colonoflor reagent kit for its implementation.

The patent was issued in October 2022 by the Federal Service for Intellectual Property.

Colonoflor reagent kits: included with Colonoflor Metabolism, Colonoflor Biocenosis, and Colonoflor Premium, are designed to quantitatively analyze the composition of the colon microbiota using Real-Time PCR in children and adults. The test system detects the DNA of obligate microflora (bifidobacteria, lactobacilli, and E. coli), as well as opportunistic microorganisms.

The use of PCR allows for a wider range of detectable microorganisms. This method is significantly more effective than bacteriological methods in identifying anaerobic flora, which are important to clinicians, and also offers several advantages over traditional bacteriological testing:

  1. Speed ​​of execution.
  2. Less stringent preanalytical requirements.
  3. Efficient in detecting anaerobic microorganisms.
  4. Detection of bacterial markers for colorectal cancer.

Reagent kits Colonoflor